Mouse Gene Unc93b1 (ENSMUST00000162708.6) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus unc-93 hom*olog B1, TLR signaling regulator (Unc93b1), transcript variant 1, mRNA. (from RefSeq NM_019449) Gencode Transcript: ENSMUST00000162708.6 Gencode Gene: ENSMUSG00000036908.17 Transcript (Including UTRs) Position:mm10 chr19:3,935,186-3,949,340Size:14,155Total Exon Count:11Strand:+ Coding Region Position:mm10 chr19:3,935,194-3,948,942Size:13,749Coding Exon Count:11
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Comments and Description Text from UniProtKB
ID: E9PYK0_MOUSE DESCRIPTION: SubName: Full=Protein unc-93 hom*olog B1; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. |
Primer design for this transcript
Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA. Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence. To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3 |
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have. |
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR010291 - Ion_channel_UNC-93 Pfam Domains: ModBase Predicted Comparative 3D Structure on E9PYK0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene. |
Gene Ontology (GO) Annotations with Structured Vocabulary
Biological Process: GO:0034138 toll-like receptor 3 signaling pathway GO:0034154 toll-like receptor 7 signaling pathway GO:0034162 toll-like receptor 9 signaling pathway Cellular Component: |
Descriptions from all associated GenBank mRNAs
BC018388 - Mus musculus unc-93 hom*olog B1 (C. elegans), mRNA (cDNA clone MGC:25627 IMAGE:4209296), complete cds. AK039526 - Mus musculus adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330055C13 product:unc-93 hom*olog B (C. elegans), full insert sequence. AK030488 - Mus musculus adult male pituitary gland cDNA, RIKEN full-length enriched library, clone:5330418K19 product:UNC-93 RELATED PROTEIN (FRAGMENT) hom*olog [Mus musculus], full insert sequence. AK165060 - Mus musculus 2 days pregnant adult female oviduct cDNA, RIKEN full-length enriched library, clone:E230029A13 product:unc-93 hom*olog B (C. elegans), full insert sequence. AK155556 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630323L01 product:unc-93 hom*olog B (C. elegans), full insert sequence. AK162535 - Mus musculus adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530090P06 product:unc-93 hom*olog B (C. elegans), full insert sequence. AJ422144 - Mus musculus partial mRNA for UNC-93B protein (unc-93B gene). U89424 - Mus musculus strain BALB/c unc-93 related protein mRNA, partial cds. BC025587 - Mus musculus unc-93 hom*olog B1 (C. elegans), mRNA (cDNA clone IMAGE:5324818), complete cds. AK160499 - Mus musculus adult male tongue cDNA, RIKEN full-length enriched library, clone:2310004D13 product:unc-93 hom*olog B (C. elegans), full insert sequence. BC023731 - Mus musculus unc-93 hom*olog B1 (C. elegans), mRNA (cDNA clone MGC:38492 IMAGE:5352340), complete cds. |
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO) Protein E9PYK0 (Reactome details) participates in the following event(s): R-MMU-1678921 Full-length TLR3/7/8/9 binds to UNC93B1 |
Alternate Gene Symbols: E9PYK0, E9PYK0_MOUSE, NM_019449, uc008fxs.1, uc008fxs.2 UCSC ID: uc008fxs.2 RefSeq Accession: NM_019449 Protein: E9PYK0CCDS: CCDS29404.2 |